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Podcast

The GuideLine Ep 6: What's next in healthcare innovation? An insider's view

Featuring guest Cris Ross, Healthcare Advisor, Investor, and Author

November 02, 2026
GuideLine Podcast Episode
November 02, 2026

Read full transcript


 

Episode Overview

Healthcare’s digital transformation has opened the door to a new wave of innovation, and the possibilities are only expanding. In this episode of The GuideLine, host Stuart Brown sits down with Cris Ross, former CIO at Mayo Clinic and healthcare advisor, investor, and author, to explore exciting ways that health systems are using AI to deliver higher-quality care, more efficiently.  

From Mayo Clinic’s massive pre-COVID EHR transformation to opportunities emerging around platforms like Epic, Cris offers an insider’s view of where healthcare technology has been and where it could go next. Cris and Stuart dig into AI’s potential to make the patient experience more human, the role of governance as innovation accelerates, and one critical question every healthcare startup should ask before betting on the next big idea. 

 

 

About the host 

Headshot of bearded man in suit and tie with American flag lapel pin

Stuart Brown, Chief Transformation Officer, Guidehouse 

Stuart Brown is a celebrated technologist and thought leader with nearly three decades of transformative leadership experience across diverse industries. As Chief Transformation Officer (CXO) he leads Guidehouse’s AI-enabled transformation strategy, driving innovation to help clients accelerate transformation, modernize operations, and realize value faster. 

 

About the guest 

Professional headshot of a smiling bald man wearing glasses, a navy suit, and patterned tie indoors.

Cris Ross, Healthcare Advisor, Investor, and Author 

Cris Ross is a healthcare technology leader who previously served as Chief Information Officer at Mayo Clinic, CVSHealth / MinuteClinic, and Optum Behavioral Health. A former board chair of Healthcare Information Management Systems Society (HIMSS) and advisor to several U.S. federal health agencies, Cris currently works as a venture partner with Aegis Ventures and a senior advisor to venture capital firm Insight Partners. He co-authored the book Diagnosed and speaks frequently on AI, advanced data management, and patient-centered care.

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